Research Focus
The focus of the lab is to discover how G-protein coupled receptor systems regulate different neurological functions especially anxiety, pain, and addiction. One of the research projects involves characterization of a novel neuropeptide-receptor system, BigLEN-GPR171, and how it regulates responses to stress and reward. The second project involves understanding how different opioids alleviate pain via different mechanisms, which lead to differences in the development of tolerance and addiction. We use behavioral, biochemical, and genetic approaches toward development of novel therapeutics to better treat these disorders.
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